Short regulatory and thymic peptides
Thymalin
Thymalin is a peptide preparation obtained from thymus tissue. The supplier describes it as a bovine thymic peptide fraction with an average component size of about 500 Da, so it is a mixture and not a single defined molecule.
- TypePeptide fraction (mixture)
- Vesta listings1
Reference page for laboratory use · updated 2026-10-30
Overview
Thymalin at a glance
Thymalin was developed in Russia from calf thymus and appears in the Russian-language literature from the 1980s. Recent papers from the Saint Petersburg Institute of Bioregulation and Gerontology describe it as a polypeptide extract of thymus and report the dipeptides Lys-Glu and Glu-Trp as active components.
Thymalin should not be confused with two other thymic peptides. Thymosin alpha 1 is a defined 28-residue peptide, and thymulin is a defined nine-residue peptide that binds zinc. Thymalin is a mixture of short peptides and has neither a sequence nor a molecular weight of its own.
Vesta lists one product called Thymalin/Thymulin, supplied as a kit of 10 vials at 10 mg per vial. The batch documents should say which of the two it contains. The thymulin page gives the verified data for the defined peptide.
Composition
What the listing does not say
The supplier describes Thymalin as a bovine thymic peptide fraction with an average component size of about 500 Da. It is not itemised into defined components, so the table of masses used for single peptides does not apply.
Identity
Identity data
| Name | Thymalin |
|---|---|
| Also written as | Thymalin peptide complex, Thymic peptide fraction |
| Type | Peptide fraction (mixture) |
| Research area | Short regulatory and thymic peptides |
| Components | Not itemised by the manufacturer |
This is a mixture whose ingredients are not itemised by the manufacturer, so no formula or molecular weight can be given. Reference data retrieved on 2026-10-30. Compare these values with the batch certificate of analysis, using the compound identity file template.
Quality
Analytical notes for batch documents
- A mixture of peptides does not give one sharp HPLC peak or one intact mass. Identity is shown by a characteristic chromatographic profile compared with a reference batch, by the mass distribution, or by measuring marker peptides such as Lys-Glu and Glu-Trp.
- An area-percentage purity figure does not mean the same thing for a mixture as for a single peptide. Ask what the percentage refers to and which peaks were counted.
- The figure of about 500 Da is an average over many components. It is not a molecular weight and cannot be used to calculate the number of molecules in a vial.
- If the vial contains thymulin instead, expect one main peak with the mass given on the thymulin page. The two outcomes are easy to tell apart by LC-MS.
- The molecular weight of a vial of powder includes counter-ions and water; the share of the powder that is peptide is the net peptide content.
Vesta listings
Thymalin formats and prices
| Product | Per vial | SKU | Price per kit | Price per vial |
|---|---|---|---|---|
| Thymalin/Thymulin | 10 mg | TY10 | $108.21 | $10.82 |
Vesta lists one product called Thymalin/Thymulin. Confirm from the batch documents which of the two it contains.
Prices are per kit of 10 vials in US dollars. Shipping is paid by the customer and is shown in the cart. Volume savings of 5 %, 8 % and 10 % apply from $350.00, $600.00 and $1,000.00. See the full price list.
Published literature
Selected scientific literature
Bibliographic details were read from PubMed on 2026-10-30. The papers are listed for scientific reference; Vesta makes no claim about the use of its research materials in people or animals.
- The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19Linkova N, Khavinson V, Diatlova A et al. · Int J Mol Sci · 2023 · PMID 37686182
- Thymalin: Activation of Differentiation of Human Hematopoietic Stem CellsKhavinson VK, Linkova NS, Kvetnoy IM et al. · Bull Exp Biol Med · 2020 · PMID 33237528
- Age-related changes of thymalin content in human epidermisKhlystova ZS, Kalinina II, Shmeleva SP et al. · Bull Exp Biol Med · 2002 · PMID 12447484
Questions
Frequently asked questions
What is Thymalin?
Thymalin is a peptide preparation obtained from thymus tissue. The supplier describes it as a bovine thymic peptide fraction with an average component size of about 500 Da, so it is a mixture and not a single defined molecule.
How can I check the identity of a batch of Thymalin?
Ask for the HPLC profile and the mass distribution of the batch, compare them with a reference batch or with the marker peptides named by the supplier, and confirm that the batch code on the report matches the vial.
Which Thymalin products does Vesta list?
Vesta lists 1 product for Thymalin: 10 mg per vial in kits of 10 vials. Prices are shown per kit in US dollars, and shipping is paid by the customer.
What is Thymalin?
Thymalin is a peptide preparation obtained from thymus tissue. The supplier describes it as a bovine thymic peptide fraction with an average component size of about 500 Da. It is a mixture and not a single molecule.
Is Thymalin the same as thymulin?
No. Thymulin is a defined nine-residue peptide, pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn, that binds zinc. Thymalin is a mixture of short peptides from thymus. Vesta lists one product under the combined name Thymalin/Thymulin, so confirm from the batch documents which one the vial contains.
Does Thymalin have a molecular weight?
No single value applies. The supplier gives an average component size of about 500 Da, which describes the mixture and not one molecule.