What is Vitamin B12 Methylcobalamin 10mg/mL?
Vitamin B12 Methylcobalamin 10mg/mL (High-concentration injectable bioactive cobalamin) is methylcobalamin at 10× the standard 1mg/mL concentration — providing a high-dose B12 formulation for research protocols requiring concentrated methylcobalamin delivery. The active, methyl-donor form of B12 — coenzyme for methionine synthase and methylmalonyl-CoA mutase. Essential for myelin synthesis, DNA methylation, homocysteine metabolism, and nerve regeneration research. Higher concentration reduces injection volume for equivalent dose.
Research Applications
High-Dose B12 Neuroregeneration
Pharmacological B12 doses in peripheral nerve injury and neuropathy repair research models
Methylation Cycle Research
Methionine synthase coenzyme — high-dose homocysteine → methionine methylation kinetics
Concentrated Dose Pharmacokinetics
10mg/mL vs 1mg/mL — serum cobalamin peak, tissue distribution, and urinary excretion
Myelin Synthesis
B12 in oligodendrocyte and Schwann cell myelination — central and peripheral nervous system
B12 Deficiency Rapid Repletion
High-concentration injectable for rapid serum B12 repletion in severe deficiency research
Quick Specs
| Form | Injectable solution |
| Concentration | 10mg/mL methylcobalamin |
| CAS | 13422-55-4 |
| Molecular Formula | C₆₃H₉₁CoN₁₃O₁₄P |
| MW | 1344.4 Da |
| Purity | ≥99% by HPLC — every batch |
| Identity | MS confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Vehicle | Sterile aqueous solution |
| Storage | 2–8°C | Protect from light | Do not freeze |
| Shelf Life | 24 months (unopened) |