What is Topamac 50mg (TOPIRAMATE)?
Anticonvulsant for partial and generalized seizures and migraine prevention. Off-label for weight loss, bipolar disorder, PTSD, and alcohol use disorder. Component of Qsymia for obesity.
How it Works
Multiple mechanisms: sodium channel blockade, GABA-A agonism, AMPA/kainate glutamate receptor antagonism, carbonic anhydrase inhibition. Weight loss via appetite suppression.
Quick Specs
- Form
- Oral tablets — pre-dosed
- Active Ingredient
- TOPIRAMATE
- Dose per Tablet
- 50MG
- Pack Size
- 10×10 (100 tablets)
- Storage
- Room temperature (15–25°C), cool dry place
- Shelf Life
- 2–3 years (properly stored)
Common Side Effects
Cognitive side effects (‘Dopamax’ — word-finding difficulty, slowed thinking), paresthesia, kidney stones, weight loss, acute angle-closure glaucoma (rare emergency).
Safety Warnings
Acute angle-closure glaucoma — stop IMMEDIATELY if eye pain/visual changes and seek emergency care. Metabolic acidosis monitoring. TERATOGENIC (cleft palate). Adequate fluid intake reduces kidney stone risk. International shipping: 7–14 days

