What is Vitamin B12 Methylcobalamin 1mg/mL?
Vitamin B12 Methylcobalamin 1mg/mL (Injectable bioactive cobalamin — research grade) is methylcobalamin — the active, methyl-donor form of B12 — in aqueous injectable solution. Unlike cyanocobalamin, methylcobalamin is the biologically active coenzyme form requiring no conversion. Essential coenzyme for methionine synthase (homocysteine → methionine methylation cycle) and methylmalonyl-CoA mutase (odd-chain fatty acid metabolism). Critical for myelin synthesis, neural function, DNA methylation, and red blood cell production.
Research Applications
Methylation Cycle Research
Methionine synthase coenzyme — homocysteine to methionine conversion and SAM cycle
Neurological & Myelin Research
B12 in Schwann cell myelination — peripheral neuropathy, nerve regeneration, and neurological function
DNA Methylation
SAM-dependent methylation — epigenetic regulation, gene expression, and cell differentiation
B12 Deficiency Models
Injectable B12 for rapid repletion in pernicious anaemia and malabsorption research models
Methylcobalamin vs Cyanocobalamin
Active methylcobalamin direct bioavailability vs cyanocobalamin hepatic conversion requirement
Quick Specs
| Form | Injectable solution |
| Concentration | 1mg/mL methylcobalamin |
| CAS | 13422-55-4 |
| Molecular Formula | C₆₃H₉₁CoN₁₃O₁₄P |
| MW | 1344.4 Da |
| Purity | ≥99% by HPLC — every batch |
| Identity | MS confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Vehicle | Sterile aqueous solution |
| Storage | 2–8°C | Protect from light | Do not freeze |
| Shelf Life | 24 months (unopened) |