What is Vardenafil?
Vardenafil (Levitra — high-selectivity PDE5 inhibitor) is a Small molecule C₂₃H₃₂N₆O₄S·HCl, MW 579.1. Potent PDE5 inhibitor with higher selectivity for PDE5 over PDE6 (colour vision interference) compared to sildenafil. Prevents cGMP degradation in vascular smooth muscle via NO pathway. Short half-life (~4–5hr).
Hepatically metabolised (CYP3A4 — relevant for drug interaction research).
Research Applications
High PDE5/PDE6 Selectivity Lower visual side effects vs sildenafil — selectivity research cGMP/NO Pathway Smooth muscle vasodilation, blood flow, endothelial interaction Short-Acting PK 4–5hr half-life — rapid onset and clearance pharmacokinetics CYP3A4 Interaction Drug-drug interaction research at CYP3A4 metabolic site vs Tadalafil Short-acting (vardenafil) vs long-acting (tadalafil) PDE5 comparison
Quick Specs
- Form
- Oral tablets — pre-dosed
- Purity
- ≥99% by HPLC — every batch
- CAS Number
- 224785-91-5
- Identity
- MS molecular weight confirmed — every batch
- Peptide Type
- Phosphodiesterase Type 5 (PDE5) Inhibitor
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house Fmoc SPPS — Qingdao, China
- Storage
- Room temperature (15–25°C), cool and dry
- Shelf Life
- As indicated by manufacturer
Certificate of Analysis (COA)
✓ Verify on Janoshik
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
Domestic shipping: USA 5–7 days International shipping: 7–14 days