What is Telmisartan?
Telmisartan is an AT1R antagonist with unique secondary pharmacology: partial PPARγ agonism — unique among ARBs, producing metabolic benefits (insulin sensitisation, adiponectin upregulation) without full PPARγ agonist side effects. Research: RAS pharmacology, dual AT1R/PPARγ biology, metabolic-cardiovascular interaction, longevity. CAS 144701-48-4.
Research Applications
AT1R Antagonism Angiotensin II blockade — RAS pharmacology, cardiac remodelling PPARγ Partial Agonism Unique among ARBs — metabolic benefits, insulin sensitisation Metabolic-Cardiovascular Dual RAS/PPARγ — comparative vs pure ARBs and TZDs Longevity Research RAS blockade extends lifespan in rodent ageing models Renal Protection AT1R-mediated renal fibrosis, podocyte protection, diabetic nephropathy
Quick Specs
- Form
- Tablet — 40mg per tablet, 100-tablet bottle
- CAS Number
- 144701-48-4
- Molecular Formula
- C₃₃H₃₀N₄O₂ Molecular Weight 514.6 g/mol
- Compound Type
- AT1R antagonist / PPARγ partial agonist
- Purity
- ≥99% by HPLC — every batch
- Identity
- MS molecular weight confirmed — every batch
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house synthesis — Qingdao, China
- Storage
- Room temperature sealed | cool, dry storage
- Shelf Life
- 24 months unopened
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
Domestic shipping: USA 5–7 days International shipping: 7–14 days

