What is TB-500 Fragment?
TB-500 Fragment is the active actin-binding domain of Thymosin Beta-4. Binds G-actin, modulates cell migration, accelerates wound healing and angiogenesis, and reduces pro-inflammatory cytokines. Research use only.
Research Applications
Wound Healing & Tissue Repair
Cell migration assays, extracellular matrix remodelling, fibroblast activity
Angiogenesis Research
Endothelial tube formation, VEGF interaction, neovascularisation models
Anti-Inflammatory Studies
Cytokine suppression, NF-κB pathway modulation, macrophage polarisation
Muscle & Tendon Recovery
Satellite cell activation, myocyte repair, tendon fibroblast proliferation
Cardiac Research
Cardiomyocyte regeneration, post-infarct remodelling studies
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 107761-42-2 |
| Molecular Formula | C₂₁H₃₈N₈O₇S, MW 562.6 |
| Identity | MS molecular weight confirmed — every batch |
| Peptide Type | Actin-Binding Recovery Peptide |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (4 weeks) |
| Shelf Life | 24 months (unopened) |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute TB-500 Fragment?
Add 1–2 mL bacteriostatic water to the lyophilized vial, directing the liquid down the inner wall. Swirl gently — do not shake. The peptide dissolves readily within 1–2 minutes.
How should TB-500 Fragment be stored?
Store lyophilized vials at −20°C. Reconstituted solution is stable at 2–8°C for up to 4 weeks. Minimize freeze-thaw cycles and light exposure.
What purity is Vesta TB-500 Fragment?
Vesta TB-500 Fragment is ≥99% pure by HPLC on every batch, with MS confirmation of molecular weight and independent Janoshik COA.
Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
International shipping: 7–14 days