What is Tamoxifen?
Tamoxifen is a first-generation triphenylethylene SERM — ER antagonist in breast tissue, partial ER agonist in bone/liver/uterus. Metabolised to endoxifen (CYP2D6) — the primary active metabolite. Also the most widely used inducer for tamoxifen-inducible CreERT2/loxP conditional knockout mouse models. CAS 10540-29-1.
Research Applications
Breast Cancer Research ER antagonist in mammary tissue — foundational hormone-sensitive cancer SERM Pharmacology Tissue-selective ERα/ERβ agonism/antagonism — bone, liver, uterus vs breast Tamoxifen-Inducible Cre Primary inducing agent for CreERT2/loxP conditional knockout models CYP2D6 Metabolism Endoxifen activation — pharmacogenomic metabolism research HPG Axis Hypothalamic ER antagonism → LH/FSH restoration in PCT models
Quick Specs
- Form
- Tablet — 20mg per tablet, 100-tablet bottle
- CAS Number
- 10540-29-1
- Molecular Formula
- C₂₆H₂₉NO Molecular Weight 371.5 g/mol
- Compound Type
- SERM / Aromatase Inhibitor
- Purity
- ≥99% by HPLC — every batch
- Identity
- MS molecular weight confirmed — every batch
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house synthesis — Qingdao, China
- Storage
- Room temperature sealed | cool, dry storage
- Shelf Life
- 24 months unopened
Certificate of Analysis (COA)
✓ Verify on Janoshik
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
Domestic shipping: USA 5–7 days International shipping: 7–14 days