What is T4 Levothyroxine?
Levothyroxine (T4) is the primary secretory product of the thyroid gland — a prohormone requiring peripheral conversion to T3 (by deiodinase DIO1/DIO2) for full activity. Research: prohormone conversion biology, DIO1/DIO2 enzyme research, hypothyroid replacement models, T4/T3 axis feedback. CAS 51-48-9.
Research Applications
Prohormone Conversion T4→T3 via DIO1/DIO2 deiodinase — peripheral thyroid activation Deiodinase Biology DIO1/DIO2/DIO3 substrate and enzyme research Hypothyroid Replacement Standard replacement model — T4 vs T4+T3 combination Thyroid Axis Feedback TRH/TSH/T4/T3 feedback loop regulation T4 vs T3 Comparison Prohormone vs active hormone — direct pharmacological comparison
Quick Specs
- Form
- Tablet — 40mcg per tablet, 100-tablet bottle
- CAS Number
- 51-48-9
- Molecular Formula
- C₁₅H₁₁I₄NO₄ Molecular Weight 776.87 g/mol
- Compound Type
- Thyroid Hormone
- Purity
- ≥99% by HPLC — every batch
- Identity
- MS molecular weight confirmed — every batch
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house synthesis — Qingdao, China
- Storage
- Room temperature sealed | cool, dry storage
- Shelf Life
- 24 months unopened
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
International shipping: 7–14 days