What is SLU-PP-332?
SLU-PP-332 is a potent synthetic agonist of estrogen-related receptors alpha and gamma (ERRα/ERRγ) — nuclear receptors that regulate mitochondrial biogenesis, oxidative phosphorylation, and fatty acid oxidation.
Produces a systemic exercise-mimetic transcriptional programme: upregulates PGC-1α co-activation, increases mitochondrial content in skeletal muscle, and enhances running endurance in mice without training. CAS 2034285-61-3.
Research Applications
ERRα/ERRγ Pharmacology Nuclear receptor agonism — ligand binding, co-activator recruitment Mitochondrial Biogenesis PGC-1α co-activation → OXPHOS gene programme Exercise Mimicry Endurance enhancement in sedentary mice — treadmill models Fatty Acid Oxidation CPT1/HADHA upregulation — skeletal muscle lipid utilisation Heart Failure Research Cardiac mitochondrial restoration in pressure-overload models
Quick Specs
- Form
- Tablet — 20mg per tablet, 100-tablet bottle
- CAS Number
- 2034285-61-3
- Molecular Formula
- C₂₅H₂₃F₃N₂O₃S Molecular Weight 492.5 g/mol
- Compound Type
- ERRα/ERRγ Nuclear Receptor Agonist
- Purity
- ≥99% by HPLC — every batch
- Identity
- MS molecular weight confirmed — every batch
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house synthesis — Qingdao, China
- Storage
- Room temperature sealed | cool, dry storage
- Shelf Life
- 24 months unopened
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
Domestic shipping: USA 5–7 days International shipping: 7–14 days