What is Sildenafil?
Sildenafil (Viagra/Revatio) is the first-in-class PDE5 inhibitor — selective for PDE5 over PDE6 (10×) and PDE1 (80×). Half-life ~4hr — suitable for acute response and dose-response studies. FDA-approved for erectile dysfunction and PAH (Revatio). Reference compound for NO/cGMP pathway research. CAS 139755-83-2.
Research Applications
NO/cGMP Reference Compound First-in-class PDE5 inhibitor — foundational cGMP signalling Acute PDE5 Inhibition 4hr half-life — acute onset/offset and dose-response kinetics Pulmonary Hypertension Revatio indication — pulmonary vascular resistance research PDE Selectivity Profile PDE5 vs PDE6 vs PDE1 selectivity — comparative PDE pharmacology vs Tadalafil Comparison Short-acting vs long-acting PDE5 — duration studies
Quick Specs
- Form
- Tablet — 100mg per tablet, 100-tablet bottle
- CAS Number
- 139755-83-2
- Molecular Formula
- C₂₂H₃₀N₆O₄S Molecular Weight 474.6 g/mol
- Compound Type
- PDE5 Inhibitor
- Purity
- ≥99% by HPLC — every batch
- Identity
- MS molecular weight confirmed — every batch
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house synthesis — Qingdao, China
- Storage
- Room temperature sealed | cool, dry storage
- Shelf Life
- 24 months unopened
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
Domestic shipping: USA 5–7 days International shipping: 7–14 days