What is Semaglutide?
Semaglutide is a long-acting GLP-1 receptor agonist with C18 fatty diacid modification enabling albumin binding and extending half-life to ~7 days. Oral tablet formulation uses SNAC (sodium caprate) absorption enhancer for gastric uptake.
Research tool for GLP-1R pharmacology, metabolic disease models, cardiovascular outcomes, and oral peptide bioavailability research. Research use only.
Research Applications
GLP-1R Pharmacology Receptor binding, cAMP/PKA activation, β-arrestin recruitment, receptor internalisation Oral Peptide Bioavailability SNAC-mediated gastric absorption, oral vs subcutaneous PK comparison Metabolic Disease Research T2DM models, HbA1c reduction, insulin secretion, glucagon suppression Cardiovascular Outcomes MACE reduction mechanisms, endothelial protection, cardiac inflammation Weight & Appetite Research Hypothalamic satiety signalling, energy intake reduction, fat mass models
Quick Specs
- Form
- Tablet — 500mcg per tablet, 25-tablet bottle
- CAS Number
- 910463-68-2
- Molecular Formula
- C₁₈₇H₂₉₁N₄₅O₅₉ Molecular Weight ~4113.6 Da
- Compound Type
- GLP-1 Receptor Agonist (Fatty Acid-Modified)
- Purity
- ≥99% by HPLC — every batch
- Identity
- MS molecular weight confirmed — every batch
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house synthesis — Qingdao, China
- Storage
- Room temperature sealed | cool, dry storage | protect from moisture
- Shelf Life
- 24 months unopened
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
International shipping: 7–14 days