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PTD-DBM 5mg | 20-Vial Kit | Wnt/CXXC5 Pathway Modulator
Anti-Aging & LongevityChinaCosmetics

PTD-DBM 5mg | 20-Vial Kit | Wnt/CXXC5 Pathway Modulator

$590

In stock

For in vitro laboratory research only. Not for human or veterinary consumption.

China Warehouse PTD-DBM 5mg | 10-Vial Kit | Wnt pathway activator via CXXC5-Dishevelled interaction disruption — hair follicle regeneration and skin wound healing research. ≥99% HPLC, Janoshik COA. Research use only. International shipping: 7–14 days

SKU
VES-PTD5-PTD-DBM-5MG-20VIAL
Format
0.22 lbs
Use
Laboratory research only
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What is PTD-DBM?

PTD-DBM is a cell-penetrating peptide construct combining a Protein Transduction Domain (PTD) and a Dvl-binding motif (DBM). It blocks the inhibitory CXXC5–Dishevelled interaction, restoring Wnt/β-catenin signalling. Studied for dermal papilla cell activation, hair follicle neogenesis, and wound healing. Research use only.

Research Applications

Wnt/β-Catenin Pathway Research

β-catenin nuclear translocation, TCF/LEF reporter assays, pathway activation

Hair Follicle Regeneration

Dermal papilla cell proliferation, anagen induction, follicle neogenesis models

Skin Wound Healing

Keratinocyte re-epithelialisation, fibroblast migration, ECM deposition

CXXC5 Biology

Wnt suppressor interaction, negative feedback loop, Dkk1 regulation

Cell-Penetrating Peptide Research

PTD transduction efficiency, intracellular delivery, nuclear targeting

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 2411025-13-3
Molecular Formula Proprietary peptide construct (PTD + DBM fusion)
Identity MS molecular weight confirmed — every batch
Peptide Type Wnt/CXXC5 Pathway Modulator
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (3 weeks)
Shelf Life 24 months (unopened)

Certificate of Analysis (COA)

Frequently Asked Questions

How do I reconstitute PTD-DBM?
Add 1 mL bacteriostatic water to the lyophilized vial, directing liquid down the inner wall. Swirl gently until clear. PTD-DBM dissolves readily within 1–2 minutes due to its hydrophilic PTD domain.
How should PTD-DBM be stored?
Store lyophilized vials at −20°C. Reconstituted solution is stable at 2–8°C for up to 3 weeks. Minimize light exposure and freeze-thaw cycles to preserve the PTD structure.
How does PTD-DBM activate Wnt signalling?
PTD-DBM contains a Dishevelled-binding motif (DBM) that competitively disrupts the inhibitory CXXC5–Dvl interaction. This relieves suppression of the Wnt/β-catenin cascade, promoting target gene transcription. The PTD domain enables intracellular delivery without transfection.
Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
International shipping: 7–14 days
Research use only

This material is supplied strictly for in vitro laboratory research. It is not intended for human or veterinary consumption, diagnosis, treatment, or household use.