What is Prednisone?
Prednisone is a synthetic glucocorticoid prodrug — converted hepatically to active prednisolone. Binds the glucocorticoid receptor (GR) with high affinity, mediating broad anti-inflammatory and immunosuppressive effects via genomic (GRE transactivation/transrepression) and non-genomic pathways.
Research tool for GR pharmacology, inflammatory cascade modelling, HPA axis studies, and immunosuppression research. Research use only.
Research Applications
Glucocorticoid Receptor Pharmacology GR binding, nuclear translocation, GRE-mediated transactivation/transrepression Anti-Inflammatory Research NF-κB suppression, AP-1 inhibition, COX-2/PLA2 downregulation, cytokine profiling HPA Axis Suppression Cortisol suppression, ACTH feedback, adrenal insufficiency models Immunosuppression Models T-cell, B-cell, macrophage suppression — transplant tolerance research Glucocorticoid-Induced Osteoporosis Osteoblast suppression, bone turnover markers, fracture risk modelling
Quick Specs
- Form
- Tablet — 10mg per tablet, 100-tablet bottle
- CAS Number
- 53-03-2
- Molecular Formula
- C₂₁H₂₆O₅ Molecular Weight 358.4 g/mol
- Compound Type
- Synthetic Glucocorticoid / Corticosteroid
- Purity
- ≥99% by HPLC — every batch
- Identity
- MS molecular weight confirmed — every batch
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house synthesis — Qingdao, China
- Storage
- Room temperature sealed | cool, dry storage
- Shelf Life
- 24 months unopened
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
International shipping: 7–14 days