What is Pancragen?
Pancragen is a tetrapeptide bioregulator from the Khavinson programme targeting pancreatic tissue. Studied for islet β-cell gene expression normalisation, exocrine function, and age-related pancreatic decline. Research use only.
Research Applications
Islet & Beta Cell Research
Insulin gene expression, glucose-stimulated insulin secretion, β-cell survival
Pancreatic Geroprotection
Age-related islet atrophy, fibrosis prevention, regeneration models
Exocrine Pancreas Studies
Acinar cell function, digestive enzyme production, inflammation
Diabetes & Metabolic Models
β-cell mass restoration, streptozotocin models, glucose homeostasis
Epigenetic Regulation
Chromatin accessibility in islet cells, Pdx1 expression, gene normalisation
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | N/A — proprietary tetrapeptide |
| Molecular Formula | Lys-Glu-Asp-Gly tetrapeptide |
| Identity | MS molecular weight confirmed — every batch |
| Peptide Type | Pancreatic Tissue Bioregulator |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (4 weeks) |
| Shelf Life | 24 months (unopened) |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute Pancragen?
Add 1–2 mL bacteriostatic water to the lyophilized vial and swirl gently. Dissolves within 1 minute.
How should Pancragen be stored?
Store lyophilized vials at −20°C. Reconstituted solution is stable at 2–8°C for up to 4 weeks.
What pancreatic cells does Pancragen target?
Pancragen research focuses primarily on islet cells (endocrine pancreas) including β-cells, but also shows activity in exocrine (acinar) tissue. As a Khavinson bioregulator, it is designed for tissue-specific gene expression normalisation.
Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
International shipping: 7–14 days