What is Letrozole?
Letrozole is a third-generation non-steroidal aromatase inhibitor (Type II — reversible competitive CYP19A1 inhibition). ~99% estrogen suppression — most potent AI. Research: estrogen-sensitive cancer, T:E2 ratio manipulation, aromatase kinetics, male hypogonadism from aromatase excess, and Type I vs Type II AI comparison. CAS 112809-51-5.
Research Applications
Aromatase Inhibition Reversible CYP19A1 competitive inhibition — ~99% estrogen suppression Hormone-Sensitive Cancer ER+ breast cancer estrogen deprivation models T:E2 Ratio Manipulation Testosterone/estradiol ratio titration in male models AI Class Comparison Non-steroidal (reversible) vs steroidal/irreversible AI mechanisms Male Hypogonadism Aromatase excess syndrome — estrogen-driven gonadotropin suppression
Quick Specs
- Form
- Tablet — 2.5mg per tablet, 100-tablet bottle
- CAS Number
- 112809-51-5
- Molecular Formula
- C₁₇H₁₁N₅ Molecular Weight 285.3 g/mol
- Compound Type
- SERM / Aromatase Inhibitor
- Purity
- ≥99% by HPLC — every batch
- Identity
- MS molecular weight confirmed — every batch
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house synthesis — Qingdao, China
- Storage
- Room temperature sealed | cool, dry storage
- Shelf Life
- 24 months unopened
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
Domestic shipping: USA 5–7 days International shipping: 7–14 days