What is Ipamorelin?
Ipamorelin (Selective GHSR-1a agonist (pentapeptide)) is a 5-amino acid synthetic pentapeptide. Highly selective ghrelin receptor (GHSR-1a) agonist stimulating GH release with minimal co-stimulation of cortisol, prolactin, or ACTH — the cleanest single-pathway GH secretagogue for research requiring isolated GHSR-1a activation without HPA axis confounds.
Research Applications
GHSR-1a Selectivity
Clean GH release without cortisol/prolactin/ACTH co-stimulation
HPA-Clean GH Research
Ideal control arm vs less selective GH secretagogues
Dual Pathway
Combined with CJC-1295 for GHRH-R + GHSR-1a synergistic GH release
Selectivity Comparison
vs GHRP-2 (moderate HPA) and GHRP-6 (full ghrelin-like profile)
Pulsatility
Amplitude vs ipamorelin dose — GH pulse characterisation
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 170851-70-4 |
| Molecular Formula | C₃₈H₄₉N₉O₅ |
| Peptide Type | Growth Hormone Secretagogue (GHRP Analog) |
| Identity | MS molecular weight confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | 24 months unopened |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute Ipamorelin?
Add 1–2mL bacteriostatic water to the lyophilized vial. Swirl gently until fully dissolved. Ipamorelin is a relatively small 5-amino acid pentapeptide and dissolves quickly. Solution should be clear and colourless.
How should Ipamorelin be stored?
Store lyophilized at −20°C. Reconstituted solution: 2–8°C for up to 28 days. Ipamorelin is reasonably stable; avoid freeze-thaw cycling of reconstituted solution and protect from light.
What purity is Vesta Ipamorelin and how is it verified?
Vesta Ipamorelin is ≥99% HPLC pure with MS confirmation of the Aib-His-D-2-Nal-D-Phe-Lys-NH₂ sequence on every batch. COA is published on the product page and verifiable at verify.janoshik.com.
Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
Domestic shipping: EU · UK · USA · AU · Canada 5–7 days
International shipping: 7–14 days