What is Hyaluronic Acid?
Hyaluronic Acid (HA) is a high-molecular-weight glycosaminoglycan and major ECM component. Binds large volumes of water, providing viscoelasticity to synovial fluid and dermal tissue. Interacts with CD44, RHAMM, and other cell-surface receptors. Research use only.
Research Applications
ECM & Biomaterial Research
Hydrogel scaffolds, tissue engineering, cell encapsulation models
Joint & Synovial Research
Viscoelasticity studies, chondrocyte proliferation, osteoarthritis models
Skin Hydration & Wound Healing
Keratinocyte migration, fibroblast activity, epidermal hydration studies
CD44 Receptor Signalling
Tumour microenvironment, cell adhesion, migration and invasion assays
Inflammatory Models
Macrophage polarisation, HA fragment signalling, TLR4 pathway
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 9004-61-9 |
| Molecular Formula | (C₁₄H₂₁NO₁₁)n — high molecular weight polysaccharide |
| Identity | MS molecular weight confirmed — every batch |
| Peptide Type | Glycosaminoglycan / ECM Biopolymer |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | 2–8°C or −20°C sealed | 2–8°C reconstituted (2 weeks) |
| Shelf Life | 24 months (unopened) |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute Hyaluronic Acid?
Add 1–2 mL sterile or bacteriostatic water to the lyophilized vial. HA forms a viscous solution — swirl gently and allow 5–10 minutes for full hydration. Do not vortex.
How should Hyaluronic Acid be stored?
Store lyophilized vials at 2–8°C or −20°C for long-term. Reconstituted solution is stable at 2–8°C for up to 2 weeks. Avoid repeated freeze-thaw cycles, which can reduce molecular weight.
What molecular weight is Vesta Hyaluronic Acid?
Vesta HA is supplied as a research-grade high-molecular-weight fraction. Exact MW and polydispersity are reported on the COA, available via Janoshik at verify.janoshik.com.
Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
International shipping: 7–14 days