What is GW501516 Cardarine?
GW501516 (Cardarine) is a selective PPARδ agonist — not a SARM (no AR activity). Activates PPARδ → GLUT4, fatty acid oxidation genes (CPT1, HADHA), and mitochondrial biogenesis in skeletal muscle. Dramatically increases running endurance in mice without training. CAS 317318-70-0.
Research Applications
PPARδ Agonism Nuclear receptor activation — fatty acid oxidation gene programme Exercise Mimicry Endurance enhancement without training — AMPK-independent Fatty Acid Oxidation CPT1/HADHA/PDHK4 upregulation — skeletal muscle lipid utilisation Mitochondrial Biogenesis PPARδ → PGC-1α co-activation — mitochondrial content increase vs AICAR/MOTS-c Comparison PPARδ vs AMPK exercise mimicry — mechanistic dissection
Quick Specs
- Form
- Tablet — 10mg per tablet, 100-tablet bottle
- CAS Number
- 317318-70-0
- Molecular Formula
- C₂₁H₁₈F₃NO₃S₂ Molecular Weight 453.5 g/mol
- Compound Type
- PPARδ Agonist
- Purity
- ≥99% by HPLC — every batch
- Identity
- MS molecular weight confirmed — every batch
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house synthesis — Qingdao, China
- Storage
- Room temperature sealed | cool, dry storage
- Shelf Life
- 24 months unopened
Certificate of Analysis (COA)
✓ Verify on Janoshik
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
Domestic shipping: USA 5–7 days International shipping: 7–14 days