What is GW-0742?
GW-0742 is a highly selective PPARδ (PPARβ/δ) agonist structurally related to GW-501516 but with improved selectivity for PPARδ over PPARα. Research tool for PPARδ-specific pathway studies, lipid oxidation research, and PPARδ vs PPARα selectivity profiling. Research use only.
Research Applications
PPARδ Selectivity Research
GW-0742 vs GW-501516 — relative PPARδ/α selectivity, isoform-specific effects
Fatty Acid Oxidation
CPT1, ACADM gene targets, skeletal muscle β-oxidation flux at selective PPARδ
Inflammation Research
PPARδ anti-inflammatory pathway — NF-κB suppression, macrophage polarisation
Metabolic Research
TG clearance, lipid homeostasis, adipose-muscle crosstalk via PPARδ
PPARδ vs PPARγ
Differential lipid and glucose handling — isoform selectivity pharmacology
Quick Specs
| Form | Raw bulk powder (crystalline/amorphous) |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 317318-84-6 |
| Molecular Formula | C₂₁H₁₇F₃NO₃S₂, MW 455.5 |
| Identity | MS molecular weight confirmed — every batch |
| Compound Type | PPARδ/β Agonist (Second-Generation) |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house synthesis — Qingdao, China |
| Storage | Room temperature sealed | cool, dry storage |
| Shelf Life | 24 months (unopened) |
Certificate of Analysis (COA)
Frequently Asked Questions
How is this raw powder supplied?
Vesta raw powder compounds are supplied as bulk crystalline or amorphous powder in a sealed, labelled container at the stated quantity. No reconstitution is required — the powder is ready for weighing and use in research applications.
How should this raw powder be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct light. Keep in the original sealed container. Properly stored raw powder remains stable for 2–3 years.
What purity is this Vesta raw powder and how is it verified?
All Vesta raw powder compounds are tested to ≥99% purity by HPLC on every production batch, with MS-confirmed identity. COA is published on the product page and independently verifiable at verify.janoshik.com.
Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
International shipping: 7–14 days