What is Fenbendazole?
Fenbendazole is a broad-spectrum benzimidazole anthelmintic that binds β-tubulin and disrupts microtubule polymerisation — the same mechanism as vinca alkaloids and other antimitotic agents.
Increasingly studied for antiproliferative effects in cancer cell lines: disrupts tubulin dynamics, interferes with glucose uptake (GLUT transporter downregulation), and activates p53 pathway. Research tool for microtubule pharmacology, antiparasitic mechanism, and emerging antineoplastic studies. Research use only.
Research Applications
Microtubule Disruption β-tubulin binding, polymerisation inhibition, mitotic spindle assembly checkpoint Antiproliferative Research Cancer cell line studies — G2/M arrest, apoptosis, p53 pathway activation Glucose Metabolism in Cancer GLUT transporter downregulation, aerobic glycolysis (Warburg effect) disruption Antiparasitic Mechanism Tubulin binding
kinetics in helminths, nematode neuromuscular paralysis reference Drug Repurposing Research Fenbendazole + conventional chemotherapy combination — in vitro sensitisation models
Quick Specs
- Form
- Tablet — 100mg per tablet, 100-tablet bottle
- CAS Number
- 43210-67-9
- Molecular Formula
- C₁₅H₁₃N₃O₂S Molecular Weight 299.4 g/mol
- Compound Type
- Benzimidazole Anthelmintic / Microtubule Disrupting Agent
- Purity
- ≥99% by HPLC — every batch
- Identity
- MS molecular weight confirmed — every batch
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house synthesis — Qingdao, China
- Storage
- Room temperature sealed | cool, dry storage
- Shelf Life
- 24 months unopened
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
International shipping: 7–14 days