What is Exemestane?
Exemestane (Aromasin — irreversible steroidal aromatase inhibitor (Type I AI)) is a Small molecule C₂₀H₂₄O₂, MW 296.4. Irreversible steroidal aromatase inhibitor (Type I, mechanism-based) that covalently inactivates CYP19A1 after single binding — unlike reversible non-steroidal AIs. Complete suppression of oestrogen synthesis in all tissues.
FDA approved for breast cancer. No rebound aromatisation after discontinuation.
Research Applications
Irreversible CYP19A1 Inactivation Mechanism-based aromatase inhibition — no enzyme recovery after binding Type I vs Type II AI Irreversible (exemestane) vs reversible (anastrozole/letrozole) comparison Oestrogen Deprivation Research Complete oestrogen suppression — breast cancer models, bone research Aromatase Biology CYP19A1 enzyme kinetics, active site interaction, inactivation mechanism Breast Cancer Research FDA-approved compound reference — hormonal breast cancer models
Quick Specs
- Form
- Oral tablets — pre-dosed
- Purity
- ≥99% by HPLC — every batch
- CAS Number
- 107868-30-4
- Molecular Formula
- C₂₀H₂₄O₂, MW 296.4.
- Identity
- MS molecular weight confirmed — every batch
- Peptide Type
- Steroidal Aromatase Inhibitor
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house Fmoc SPPS — Qingdao, China
- Storage
- Room temperature (15–25°C), cool and dry
- Shelf Life
- As indicated by manufacturer
Certificate of Analysis (COA)
✓ Verify on Janoshik
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
Domestic shipping: USA 5–7 days International shipping: 7–14 days