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Dermorphin 5mg | 20-Vial Kit | Opioid Heptapeptide | µ-Receptor Research
ChinaCognitive & Nootropic

Dermorphin 5mg | 20-Vial Kit | Opioid Heptapeptide | µ-Receptor Research

$430

In stock

For in vitro laboratory research only. Not for human or veterinary consumption.

China Warehouse Dermorphin 5mg | 20-Vial Kit — D-amino acid opioid heptapeptide — 500× higher μ-opioid receptor (MOR) affinity vs. morphine, studied for MOR pharmacology, receptor selectivity, and opioid peptide structure-activity research. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only. International shipping: 7–14 days

SKU
VES-DR5-DERMORPHIN-5MG-20VIAL
Format
0.42 lbs
Use
Laboratory research only
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What is Dermorphin??

Dermorphin (CAS 77614-16-5) is a naturally occurring heptapeptide opioid first isolated from the skin of South American frogs (Phyllomedusa sauvagei). Sequence: H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH₂. Molecular formula C₄₀H₅₀N₈O₁₀, MW 802.88 g/mol. Notably, it contains a D-alanine residue at position 2 — rare in vertebrate peptides — which confers resistance to enzymatic degradation. Dermorphin has approximately 1,000-fold greater potency at µ-opioid receptors (MOR) than morphine in preclinical binding assays, with high selectivity for MOR over δ and κ receptors. It is a fundamental research tool for opioid receptor pharmacology.

Research Applications

µ-Opioid Receptor Pharmacology

MOR binding affinity, Gi/o signalling, receptor selectivity vs. DOR/KOR profiling

Opioid Analgesia Research

Central and peripheral analgesic mechanisms, tolerance and sensitisation models

D-Amino Acid Stability

Enzymatic resistance studies — D-Ala² contribution to DPP-IV and protease stability

Receptor Signalling

cAMP suppression, GIRK channel activation, β-arrestin bias studies

Comparative Opioid Studies

Potency ratio comparisons with morphine, DAMGO, and endomorphins

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 77614-16-5
Sequence H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH₂
Molecular Formula C₄₀H₅₀N₈O₁₀
Molecular Weight 802.88 g/mol
Peptide Type Natural heptapeptide opioid / µ-MOR selective agonist
Identity MS molecular weight confirmed — every batch
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Shelf Life 24 months unopened

Certificate of Analysis (COA)

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this Vesta compound and how is it verified?
All Vesta compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
International shipping: 7–14 days
Research use only

This material is supplied strictly for in vitro laboratory research. It is not intended for human or veterinary consumption, diagnosis, treatment, or household use.