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Cagrilintide + Semaglutide Blend 10mg | 10-Vial Kit | Weight Loss Stack
ChinaPeptide BlendsUnited StatesWeight Loss & Metabolic

Cagrilintide + Semaglutide Blend 10mg | 10-Vial Kit | Weight Loss Stack

$230

In stock

For in vitro laboratory research only. Not for human or veterinary consumption.

1-Region Domestic Shipping Cagrilintide + Semaglutide Blend 10mg | 10-Vial Kit — Long-acting amylin receptor agonist — reduces food intake via area postrema satiety signalling, slows gastric emptying, and suppresses postprandial glucagon independently of GLP-1 pathways. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only. Domestic shipping: USA 5–7 days International shipping: 7–14 days

SKU
VES-CS10-CAGRILINTIDE-SEMAGLUTIDE-10MG-10VIAL
Format
0.22 lbs
Use
Laboratory research only
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What is Cagrilintide + Semaglutide Blend?

Cagrilintide + Semaglutide Blend (CagriSema — dual amylin+GLP-1 receptor co-agonism) is a Pre-blended cagrilintide + semaglutide (equimolar per vial). Pre-blended combination of cagrilintide (amylin receptor: CALCR+RAMP1/2/3) and semaglutide (GLP-1R). Dual amylin+GLP-1R activation produces additive appetite suppression via complementary brainstem (amylin) and hypothalamic (GLP-1R) circuits. CagriSema Phase 3 (REDEFINE-1, 2025): ~23% mean weight reduction.

Research Applications

Dual Amylin+GLP-1R

CALCR/RAMP + GLP-1R co-activation — complementary appetite circuits

CagriSema Phase 3 Reference

REDEFINE-1 2025 reference compound — 23% weight reduction

Additive Appetite Suppression

Beyond selective GLP-1R agonism — amylin brainstem circuits

vs Tirzepatide

Different dual mechanism: amylin+GLP-1R vs GIP+GLP-1R

Amylin Receptor Biology

CALCR/RAMP complex pharmacology alongside GLP-1R

Quick Specs

Form Pre-blended cagrilintide + semaglutide
Purity ≥99% by HPLC — every batch
CAS Number Not applicable (dual peptide combination)
Molecular Formula Sequence-specific (Cagrilintide + Semaglutide)
Peptide Type Dual Amylin Analog + GLP-1 Receptor Agonist Blend
Identity MS molecular weight confirmed — every batch
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Shelf Life 24 months unopened

Certificate of Analysis (COA)

Vesta COA Report

✓ Verify on Janoshik

Frequently Asked Questions

How do I reconstitute Semaglutide?
Add 1–2mL bacteriostatic water to the lyophilized Semaglutide vial by directing the water down the vial wall. Swirl gently until fully dissolved — do not shake. Solution should be clear and colourless. For long-acting GLP-1 research, use a 1mL insulin syringe for precise volume measurement.
How should Semaglutide be stored?
Lyophilized: −20°C long-term storage. Reconstituted: 2–8°C, use within 21–28 days. Semaglutide is relatively stable due to its C18 fatty acid modification, but avoid repeated freeze-thaw cycles. Discard if solution becomes cloudy.
What purity is Vesta Semaglutide and how is it verified?
Vesta Semaglutide is tested at ≥99% HPLC purity with mass spectrometry identity confirmation on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com.
Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
Domestic shipping: USA 5–7 days
International shipping: 7–14 days
Research use only

This material is supplied strictly for in vitro laboratory research. It is not intended for human or veterinary consumption, diagnosis, treatment, or household use.