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Botulinum Toxin 100 IU | 10-Vial Kit | SNAP-25 Cleaving Neurotoxin | Neuromuscular & Cosmetic Research
AsiaChinaCosmeticsRecovery & Healing

Botulinum Toxin 100 IU | 10-Vial Kit | SNAP-25 Cleaving Neurotoxin | Neuromuscular & Cosmetic Research

$300

In stock

For in vitro laboratory research only. Not for human or veterinary consumption.

0-Region Domestic Shipping Botulinum Toxin 100 IU | 10-Vial Kit — BoNT-A zinc-dependent metalloprotease that cleaves SNAP-25 at presynaptic neuromuscular junction, blocking acetylcholine vesicle fusion and studied for neuromuscular blockade, expression-line, and autonomic nerve research. ≥99% HPLC purity, MS confirmed. Research use only. International shipping: 7–14 days

SKU
VES-XT100-BOTOX-100IU-10VIAL
Format
0.22 lbs
Use
Laboratory research only
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What is Botulinum Toxin Type A??

Botulinum Toxin Type A (BoNT-A, CAS 93384-43-1) is a 150 kDa zinc-dependent metalloprotease produced by Clostridium botulinum. It consists of a 100 kDa heavy chain (receptor binding and membrane translocation) disulfide-linked to a 50 kDa light chain (catalytic endopeptidase). BoNT-A cleaves SNAP-25 (synaptosomal-associated protein 25 kDa) at the presynaptic neuromuscular junction – preventing SNARE complex assembly required for acetylcholine (ACh) vesicle fusion and release. This produces localised chemodenervation lasting 3-6 months until new nerve terminal sprouting restores function. BoNT-A is both the world’s most potent biological toxin and one of the most widely used therapeutics, forming the mechanistic basis for cosmetic wrinkle reduction, spasticity treatment, hyperhidrosis, migraine prophylaxis, and autonomic disorder research.

Research Applications

SNARE Complex & Neuromuscular Biology

SNAP-25 endoproteolysis, SNARE complex inhibition kinetics, ACh vesicle exocytosis blockade mechanisms

Chemodenervation Research

Motor end-plate remodelling, nerve terminal sprouting/recovery, NMJ plasticity timecourse studies

Cosmetic & Dermatology Research

Glabellar/forehead wrinkle reduction mechanisms, mimetic muscle paralysis, collagen remodelling under denervation

Spasticity & Movement Disorders

Upper motor neuron syndrome models, dystonia, cerebral palsy – focal muscle hyperactivity quantification

Autonomic & Pain Research

Hyperhidrosis sweat gland denervation, chronic migraine CGRP pathway interaction, autonomic ganglia studies

Quick Specs

Form Lyophilized powder
Purity >=99% by HPLC – every batch
CAS Number 93384-43-1
Activity 100 IU/vial (1 IU = LD50 in 18-20g female Swiss-Webster mice)
Molecular Weight ~150 kDa (heavy chain + light chain disulfide homodimer)
Mechanism SNAP-25 endoproteolysis – SNARE complex inhibition – ACh vesicle blockade
Peptide Type Bacterial zinc-dependent metalloprotease / neurotoxin serotype A
Identity MS molecular weight confirmed – every batch
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS – Qingdao, China
Storage -20C sealed | Do NOT reconstitute until use
Shelf Life 24 months unopened

Certificate of Analysis (COA)

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this Vesta compound and how is it verified?
All Vesta compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
Peptide Research Tools: Use Vesta’s free peptide calculators – reconstitution, BAC water, dosing, half-life, and mixing charts.
International shipping: 7–14 days
Research use only

This material is supplied strictly for in vitro laboratory research. It is not intended for human or veterinary consumption, diagnosis, treatment, or household use.