What is BAM15?
BAM15 is a protonophore that dissipates the mitochondrial proton gradient — uncoupling OXPHOS from ATP synthesis and driving energy dissipation as heat. Critically, BAM15 does not penetrate the plasma membrane and does not cause hyperthermia in vivo — the primary safety limitation of classical uncouplers (DNP). Romero et al.
2020: fat mass reduction and improved insulin sensitivity in DIO mice without hyperthermia. CAS 2061936-25-0.
Research Applications
Mitochondrial Uncoupling Proton gradient dissipation — heat vs ATP thermogenesis research Safe Uncoupler Reference No plasma membrane penetration — avoids DNP hyperthermia Obesity/Metabolic Romero 2020: fat mass reduction + insulin sensitivity in DIO mice UCP1 Comparison Pharmacological vs physiological (BAT UCP1) uncoupling Mitochondrial Bioenergetics OCR/ECAR (Seahorse), proton leak, coupling efficiency
Quick Specs
- Form
- Tablet — 50mg per tablet, 100-tablet bottle
- CAS Number
- 2061936-25-0
- Molecular Formula
- C₁₃H₁₈F₆N₂O₃ Molecular Weight 380.3 g/mol
- Compound Type
- Mitochondrial Uncoupler — Protonophore
- Purity
- ≥99% by HPLC — every batch
- Identity
- MS molecular weight confirmed — every batch
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house synthesis — Qingdao, China
- Storage
- Room temperature sealed | cool, dry storage
- Shelf Life
- 24 months unopened
Certificate of Analysis (COA)
✓ Verify on Janoshik
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
Domestic shipping: USA 5–7 days International shipping: 7–14 days