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B7-33 6mg | 10-Vial Kit | RXFP1 Relaxin Analogue
ChinaRecovery & Healing

B7-33 6mg | 10-Vial Kit | RXFP1 Relaxin Analogue

$330

In stock

For in vitro laboratory research only. Not for human or veterinary consumption.

China Warehouse B7-33 6mg | 10-Vial Kit | Single-chain RXFP1 agonist — relaxin B-chain analogue for anti-fibrotic, collagen remodelling, and cardiac fibrosis research. ≥99% HPLC purity, Janoshik COA. Research use only. International shipping: 7–14 days

SKU
VES-B76-B733-6MG-10VIAL
Format
0.22 lbs
Use
Laboratory research only
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What is B7-33?

B7-33 is a single-chain peptide analogue of the relaxin-2 B-chain, engineered to selectively activate RXFP1 (relaxin family peptide receptor 1) while avoiding the native two-chain structure of relaxin-2. Studied for anti-fibrotic effects, collagen remodelling, vasodilation, and cardioprotection — without the insulin-like A-chain that complicates full relaxin manufacture. Represents a simplified, single-chain RXFP1 agonist for fibrosis and cardiovascular research. Research use only.

Research Applications

Anti-Fibrotic Research

Collagen I/III expression suppression, MMP upregulation, TGF-β pathway modulation

RXFP1 Receptor Pharmacology

Receptor binding kinetics, cAMP/PKA signalling, β-arrestin recruitment

Cardiac Fibrosis Models

Post-infarct remodelling, myocardial stiffness, cardiac fibroblast activity

Vasodilation & Vascular Biology

NO-mediated vasodilation, endothelial function, arterial compliance

Single-Chain Relaxin Analogue Studies

B7-33 vs full relaxin-2 pharmacodynamic comparison, potency, selectivity

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 2413928-17-1
Molecular Formula Single-chain relaxin B-chain analogue, ~3,800 Da
Identity MS molecular weight confirmed — every batch
Peptide Type Relaxin B-Chain Peptide / RXFP1 Agonist
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (4 weeks)
Shelf Life 24 months (unopened)

Certificate of Analysis (COA)

Frequently Asked Questions

How do I reconstitute B7-33?
Add 1 mL bacteriostatic water to the lyophilized vial, directing liquid down the inner wall. Swirl gently until clear — dissolves within 1–2 minutes. The 6mg vial provides a concentrated stock suitable for dilution to working concentrations.
How should B7-33 be stored?
Store lyophilized vials at −20°C. Reconstituted solution is stable at 2–8°C for up to 4 weeks. Avoid repeated freeze-thaw cycles. B7-33 is relatively stable due to its engineered single-chain structure.
Why use B7-33 instead of native relaxin-2?
Native human relaxin-2 is a two-chain peptide (A and B chains linked by disulfide bonds) requiring complex manufacture. B7-33 achieves selective RXFP1 agonism from a single synthesisable chain, enabling more reproducible research with comparable pharmacological activity at the receptor level.
Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
International shipping: 7–14 days
Research use only

This material is supplied strictly for in vitro laboratory research. It is not intended for human or veterinary consumption, diagnosis, treatment, or household use.