What is Andarine (S4)?
Andarine (S4) is a nonsteroidal SARM with partial AR agonist activity. Originally developed by GTx as a prostate-targeted androgen. Partial agonist profile produces anabolic activity in muscle and bone with lower full-agonist efficacy than testosterone.
Notable for its partial agonism mechanism and visual side effect profile (retina AR binding) at high doses, making it a useful model compound for SARM partial agonism and tissue selectivity research. Research use only.
Research Applications
Partial AR Agonism Research Partial vs full agonist efficacy comparison — Emax, tissue selectivity, coactivator recruitment Muscle & Bone Anabolism Anabolic activity at partial agonist efficacy — lean mass, bone density models Retinal AR Research S4-mediated visual disturbances — retina AR expression, off-target tissue binding Prostate SARM Pharmacology
Partial agonist in prostate tissue — BPH model comparison with full agonists Comparative SARM Studies S4 partial agonism vs Ostarine, LGD-4033, RAD-140 full agonist — receptor pharmacology
Quick Specs
- Form
- Tablet — 25mg per tablet, 100-tablet bottle
- CAS Number
- 401900-40-1
- Molecular Formula
- C₁₉H₁₈F₃N₃O₆ Molecular Weight 441.4 g/mol
- Compound Type
- Selective Androgen Receptor Modulator (SARM)
- Purity
- ≥99% by HPLC — every batch
- Identity
- MS molecular weight confirmed — every batch
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house synthesis — Qingdao, China
- Storage
- Room temperature sealed | cool, dry storage
- Shelf Life
- 24 months unopened
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
International shipping: 7–14 days