For in vitro laboratory research only. Not for human or veterinary consumption.
0-Region Domestic Shipping Adipotide 10mg | 10-Vial Kit — Proapoptotic peptidomimetic — selectively induces apoptosis in prohibitin-expressing white adipose vasculature, causing adipocyte death via ischaemia studied in obesity models. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only. International shipping: 7–14 days
Adipotide (CKGGRAKDC-GG-D(KLAKLAK)₂ — proapoptotic adipose-targeting peptide) is a Chimeric peptide (targeting + proapoptotic domains). Bimodal chimeric peptide: CKGGRAKDC domain selectively homes to white adipose tissue vasculature; D(KLAKLAK)₂ proapoptotic domain disrupts mitochondrial membranes in targeted cells. Induces apoptosis specifically in WAT endothelial cells → secondary adipocyte death. Obese primate studies: rapid and specific WAT reduction.
Research Applications
Adipose Vasculature Targeting
CKGGRAKDC domain — selective WAT endothelial binding
Proapoptotic Mechanism
D(KLAKLAK)₂ mitochondrial membrane disruption
WAT-Selective Reduction
Targeted weight loss distinct from metabolic (GLP-1) approaches
Tissue-Targeted Delivery
Dual-domain chimeric peptide design and biodistribution research
vs Metabolic Weight Loss
Mechanistic comparison: vascular disruption vs appetite suppression
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this Vesta compound and how is it verified?
All Vesta compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
International shipping: 7–14 days
Research use only
This material is supplied strictly for in vitro laboratory research. It is not intended for human or veterinary consumption, diagnosis, treatment, or household use.
