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5-Amino-1MQ 50mg | 10-Vial Kit | NNMT Inhibitor
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5-Amino-1MQ 50mg | 10-Vial Kit | NNMT Inhibitor

$220

In stock

For in vitro laboratory research only. Not for human or veterinary consumption.

1-Region Domestic Shipping Vesta 5-Amino-1MQ (NNMT inhibitor) — ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only. Domestic shipping: USA 5–7 days International shipping: 7–14 days

SKU
VES-50AM-5AMINO1MQ-50MG-10VIAL
Format
0.22 lbs
Use
Laboratory research only
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What is 5-Amino-1MQ?

5-Amino-1MQ (5-Amino-1-methylquinolinium — NNMT inhibitor) is a Small molecule (C₁₀H₁₀N₂, MW 174.2). Competitive NNMT (nicotinamide N-methyltransferase) inhibitor preventing nicotinamide from being diverted away from the NAD+ salvage pathway. Preserves SAM methyl donor pool and improves SAM/SAH ratio for epigenetic methylation. Indirect NAD+ increase → SIRT1 activation → PGC-1α → mitochondrial biogenesis.

Research Applications

NNMT Inhibition

Competitive enzyme inhibition — NAD+ precursor preservation

Indirect NAD+ Upregulation

Salvage pathway restoration vs direct NR/NMN supplementation

Adipogenesis Suppression

PRDM16 methylation preservation → white vs brown adipocyte fate

SIRT1/PGC-1α Axis

NAD+-dependent sirtuin activation and mitochondrial biogenesis

SAM/SAH Methylation

Epigenetic methylation biology and methyl donor pool research

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 42464-96-0
Molecular Formula C₁₀H₁₁ClN₂
Peptide Type Small Molecule NNMT Inhibitor
Identity MS molecular weight confirmed — every batch
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Shelf Life 24 months sealed

Certificate of Analysis (COA)

Vesta COA Report

✓ Verify on Janoshik

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this Vesta compound and how is it verified?
All Vesta compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
Domestic shipping: USA 5–7 days
International shipping: 7–14 days
Research use only

This material is supplied strictly for in vitro laboratory research. It is not intended for human or veterinary consumption, diagnosis, treatment, or household use.