What is Nexluma 42mg (LURASIDONE)?
Atypical antipsychotic for schizophrenia and bipolar I depression. Notable for good metabolic safety profile and proven efficacy specifically in bipolar depression.
How it Works
D2 and 5-HT2A antagonist with potent 5-HT7 antagonism (cognitive and antidepressant effects) and 5-HT1A partial agonism. Lower H1 and muscarinic affinity — better metabolic profile.
Quick Specs
- Form
- Oral tablets — pre-dosed
- Active Ingredient
- LURASIDONE
- Dose per Tablet
- 42MG
- Pack Size
- 10×10 (100 tablets)
- Storage
- Room temperature (15–25°C), cool dry place
- Shelf Life
- 2–3 years (properly stored)
Common Side Effects
Akathisia, somnolence, nausea (especially early), weight gain (less than olanzapine/quetiapine), hyperprolactinemia, EPS (dose-dependent).
Safety Warnings
Take with food (at least 350 calories — greatly increases absorption). Avoid strong CYP3A4 inhibitors/inducers. Black box: increased mortality in elderly dementia patients. International shipping: 7–14 days

