What is Methylene Blue?
Methylene Blue is a phenothiazine dye with multiple pharmacological mechanisms: (1) mitochondrial electron carrier — bypasses Complex I-III by accepting electrons from NADH and donating to cytochrome c, rescuing mitochondrial dysfunction; (2) weak MAO inhibitor; (3) guanylate cyclase inhibitor; (4) tau aggregation inhibitor (Alzheimer’s research).
CAS 61-73-4.
Research Applications
Mitochondrial ETC Bypass NADH→MB→cytochrome c — Complex I/III bypass for mitochondrial rescue Cognitive Enhancement Low-dose cognitive effects — memory and attention in rodent models Alzheimer’s/Tau Research Tau aggregation inhibition — Alzheimer’s disease models Mitochondrial Rescue ETC dysfunction models — rotenone/antimycin Complex I/III blockade rescue NO/cGMP Inhibition Guanylate cyclase inhibition — NO research and vasodilation studies
Quick Specs
- Form
- Tablet — 10mg per tablet, 100-tablet bottle
- CAS Number
- 61-73-4
- Molecular Formula
- C₁₆H₁₈ClN₃S Molecular Weight 319.9 g/mol
- Compound Type
- mitochondrial electron carrier
- Purity
- ≥99% by HPLC — every batch
- Identity
- MS molecular weight confirmed — every batch
- COA
- Janoshik-independent, publicly verifiable
- Manufacture
- In-house synthesis — Qingdao, China
- Storage
- Room temperature sealed | cool, dry storage
- Shelf Life
- 24 months unopened
Certificate of Analysis (COA)
✓ Verify on Janoshik
Frequently Asked Questions
How are Vesta research tablets supplied?
Vesta research tablets are supplied as pre-dosed oral tablets at the stated concentration.
No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications. How should research tablets be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight.
Keep in the original container. Properly stored tablets remain stable for 2–3 years. What purity are Vesta research tablets and how is it verified?
Vesta research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com. Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
Domestic shipping: USA 5–7 days International shipping: 7–14 days

