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5-Amino-1MQ 5mg | 10-Vial Kit | 50mg Total | NNMT Inhibitor
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5-Amino-1MQ 5mg | 10-Vial Kit | 50mg Total | NNMT Inhibitor

$190

In stock

For in vitro laboratory research only. Not for human or veterinary consumption.

2-Region Domestic Shipping 5-Amino-1MQ 5mg — NNMT inhibitor, NAD+ elevation, fat oxidation research. ≥99% HPLC, Janoshik COA. 10-vial kit, 50mg total. Research use only. Domestic shipping: USA · Canada 5–7 days International shipping: 7–14 days

SKU
VES-5AM-5AMINO1MQ-5MG-10VIAL
Format
0.5 lbs
Use
Laboratory research only
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What is 5-Amino-1MQ 5mg?

5-Amino-1MQ (5-amino-1-methylquinolinium) is a selective, cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT). By blocking NNMT, it prevents the methylation and disposal of nicotinamide, raising intracellular NAD+ levels and activating SIRT1-mediated fat oxidation. Research applications include obesity, metabolic syndrome, and adipocyte biology.

Research Applications

Fat Oxidation & Adipocyte Research

NNMT inhibition reduces adipogenesis and promotes lipolysis in white adipose tissue. 3T3-L1 cell model standard for evaluating anti-obesity activity.

NAD+ / SIRT1 Pathway Research

Raising intracellular NAD+ activates sirtuins (SIRT1, SIRT3) — links to longevity, mitochondrial biogenesis, and glucose metabolism pathways.

Metabolic Syndrome Models

DIO mouse models: 5-Amino-1MQ reduces fat mass and improves insulin sensitivity without affecting food intake — distinct from appetite-suppression mechanisms.

Quick Specs

Product 5-Amino-1MQ 5mg × 10 Vials (50mg total)
CAS 1342278-01-6
Format Lyophilised powder, 10-vial kit
Purity ≥99% HPLC, MS confirmed
Storage −20°C lyophilised; 4°C reconstituted, 7 days
Reconstitution Bacteriostatic water or DMSO

Certificate of Analysis (COA)

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this Vesta compound and how is it verified?
All Vesta compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
Peptide Research Tools: Use Vesta’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
Domestic shipping: USA  ·  Canada 5–7 days
International shipping: 7–14 days
Research use only

This material is supplied strictly for in vitro laboratory research. It is not intended for human or veterinary consumption, diagnosis, treatment, or household use.